Anticorps Recombinant de lapin anti-NHE3

NHE3 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240999B6

N° de cat : 83832-3-PBS

Synonymes

NHE-3, SLC9A3

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Galerie de données de validation

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  Cytometric bead array standard curve of MP00818-1

  Cytometric bead array standard curve of MP00818-1, SLC9A3 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83832-2-PBS. Detection antibody: 83832-3-PBS. Standard: Ag25637. Range: 0.313-40 ng/mL.

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  Cytometric bead array standard curve of MP00818-2

  Cytometric bead array standard curve of MP00818-2, SLC9A3 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83832-5-PBS. Detection antibody: 83832-3-PBS. Standard: Ag25637. Range: 0.625-40 ng/mL.

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  Affinity and Kinetic Characterization of 83832-3-PBS

  Biolayer interferometry (BLl) kinetic assay of 83832-3-PBS against Human NHE3 was performed. The affinity constant is 0.495 nM.

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Informations sur le produit

83832-3-PBS cible NHE3 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: NHE3 Protéine recombinante Ag25637
• Nom complet: solute carrier family 9 (sodium/hydrogen exchanger), member 3
• Masse moléculaire calculée: 834 aa, 93 kDa
• Numéro d’acquisition GenBank: BC101669
• Symbole du gène: NHE3
• Identification du gène (NCBI): 6550
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC9A3, also known as NHE3, belongs to the sodium hydrogen exchange protein family (NHE) and is mainly responsible for regulating the concentration of sodium and hydrogen ions inside and outside the cell. SLC9A3 is a Major apical Na+/H+ exchanger in kidney and intestine, playing an important role in renal and intestine Na+ absorption and blood pressure regulation (PMID:24622516, 2635877). Mutations in SLC9A3 cause Congenital Sodium Diarrhea (PMID: 26358773, 31276831).

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