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Anticorps Polyclonal de lapin anti-SLCO1B3/OATP1B3

SLCO1B3/OATP1B3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22815-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using SLCO1B3/OATP1B3 Polyclonal antibody (22815-1-AP)

    WB analysis using 22815-1-AP (same clone as 22815-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22815-1-AP (SLCO1B3/OATP1B3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22815-1-PBS in a different storage buffer formulation.

Informations sur le produit

22815-1-PBS cible SLCO1B3/OATP1B3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène SLCO1B3/OATP1B3 Protéine recombinante Ag18940
Nom complet solute carrier organic anion transporter family, member 1B3
Masse moléculaire calculée 702 aa, 77 kDa
Poids moléculaire observé 70-75 kDa
Numéro d’acquisition GenBankBC105597
Symbole du gène SLCO1B3
Identification du gène (NCBI) 28234
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. SLCO1B3 is a glycosylated protein and can be detected in the non-glycosylated form at 70-75 kDa(PMID: 21278621).

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