Anticorps Recombinant de lapin anti-SLCO2B1

SLCO2B1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241199F9

N° de cat : 84353-1-PBS

Synonymes

OATPRP2, OATPB, OATP2B1, OATP B, KIAA0880

---

Galerie de données de validation

• 

  WB analysis using 84353-1-RR (same clone as 84353-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84353-1-RR (SLCO2B1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84353-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

84353-1-PBS cible SLCO2B1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: solute carrier organic anion transporter family, member 2B1
• Masse moléculaire calculée: 77 kDa
• Poids moléculaire observé: 61~74 kDa
• Numéro d’acquisition GenBank: NM_007256
• Symbole du gène: SLCO2B1
• Identification du gène (NCBI): 11309
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Solute carrier organic anion (SLCO) gene families encode organic anion transport proteins (OATP), which are membrane transporters widely expressed in the human body that influx numerous compounds and drugs including androgens. SLCO2B1 is a member of an organic anion transporter family and has previously been shown to transport a multitude of drugs and steroid hormone conjugates (PMID: 35714613). High expression of SLCO2B1 is known to associate with the resistance to androgen deprivation therapy in prostate cancer (PMID: 29581838). OATP2B1 was insensitive to endoglycosidase H, an enzyme that cleaves only high mannose glycans, as expected for a mature protein undergoing complex glycosylation.

{{ptg:RelatedPrimaryAntibodies}}