Anticorps Monoclonal anti-SMARCB1

SMARCB1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1D10A4

N° de cat : 67979-1-PBS

Synonymes

1D10A4, BAF47, BRG1-associated factor 47, hSNF5, hSNFS

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Galerie de données de validation

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  WB analysis using 67979-1-Ig (same clone as 67979-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67979-1-Ig (SMARCB1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67979-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse stomach using 67979-1-Ig (same clone as 67979-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 67979-1-Ig (SMARCB1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67979-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse stomach using 67979-1-Ig (same clone as 67979-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 67979-1-Ig (SMARCB1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67979-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67979-1-PBS cible SMARCB1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SMARCB1 Protéine recombinante Ag28911
• Nom complet: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
• Masse moléculaire calculée: 44 kDa
• Poids moléculaire observé: 40-45 kDa
• Numéro d’acquisition GenBank: NM_003073
• Symbole du gène: SMARCB1
• Identification du gène (NCBI): 6598
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SMARCB1 is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.

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