Anticorps Polyclonal de lapin anti-SMPD1,ASM

• Phare
• Validé par KD/KO

SMPD1,ASM Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14609-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 14609-1-AP (same clone as 14609-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14609-1-AP (SMPD1,ASM antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 14609-1-AP (same clone as 14609-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 14609-1-AP (same clone as 14609-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 14609-1-AP (same clone as 14609-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 14609-1-AP (same clone as 14609-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 14609-1-AP (SMPD1,ASM Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14609-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14609-1-PBS cible SMPD1,ASM dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SMPD1,ASM Protéine recombinante Ag6180
• Nom complet: sphingomyelin phosphodiesterase 1, acid lysosomal
• Masse moléculaire calculée: 70 kDa
• Poids moléculaire observé: 60 kDa, 70-75 kDa
• Numéro d’acquisition GenBank: BC041164
• Symbole du gène: SMPD1
• Identification du gène (NCBI): 6609
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SMPD1(Sphingomyelin phosphodiesterase) is also named as ASM and belongs to the acid sphingomyelinase family. It is an important enzyme in sphingolipid metabolism and plays key roles in apoptosis, immunity, development, and cancer. The deficient activity of this enzyme results in Types A and B Niemann-Pick disease (NPD). This protein has 4 isoforms produced by alternative splicing. SMPD1 can produce a 60 kDa peptide with its signal peptide missing.

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