Anticorps Polyclonal de lapin anti-SMPD3

SMPD3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25613-1-PBS

Synonymes

EC:3.1.4.12, Neutral sphingomyelinase 2, Neutral sphingomyelinase II, nSMase 2, nSMase2

---

Galerie de données de validation

• 

  WB analysis using 25613-1-AP (same clone as 25613-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 25613-1-AP (SMPD3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25613-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 25613-1-AP (same clone as 25613-1-PBS)

  K-562 cells were subjected to SDS PAGE followed by western blot with 25613-1-AP (SMPD3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25613-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

25613-1-PBS cible SMPD3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SMPD3 Protéine recombinante Ag22487
• Nom complet: sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
• Masse moléculaire calculée: 655 aa, 71 kDa
• Poids moléculaire observé: 70-71 kDa
• Numéro d’acquisition GenBank: BC112238
• Symbole du gène: SMPD3
• Identification du gène (NCBI): 55512
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SMPD3 (sphingomyelin phosphodiesterase 3), also called neutral sphingomyelinase-2 (nSMase2), is a Golgi-enriched, membrane-bound Zn²⁺-dependent hydrolase that converts sphingomyelin into ceramide and phosphocholine. Ceramide functions as a bioactive lipid second messenger that integrates cellular stress, apoptosis, autophagy and differentiation signals.

{{ptg:RelatedPrimaryAntibodies}}