Anticorps Polyclonal de lapin anti-SMYD4

• Phare
• Validé par KD/KO

SMYD4 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17594-1-PBS

Synonymes

ZMYND21, SMYD 4, SET and MYND domain-containing protein 4, EC:2.1.1.-

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Galerie de données de validation

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  WB analysis of HepG2 using 17594-1-AP (same clone as 17594-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 17594-1-AP (SMYD4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 17594-1-AP (same clone as 17594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas using 17594-1-AP (SMYD4 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas using 17594-1-AP (same clone as 17594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas using 17594-1-AP (SMYD4 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IHC staining of human hepatocirrhosis using 17594-1-AP (same clone as 17594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis using 17594-1-AP (SMYD4 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IHC staining of human hepatocirrhosis using 17594-1-AP (same clone as 17594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human hepatocirrhosis using 17594-1-AP (SMYD4 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 17594-1-AP (same clone as 17594-1-PBS)

  Immunofluorescent analysis of (-20℃ Ethanol) fixed HepG2 cells using 17594-1-AP (SMYD4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 17594-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17594-1-PBS cible SMYD4 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SMYD4 Protéine recombinante Ag11552
• Nom complet: SET and MYND domain containing 4
• Masse moléculaire calculée: 804 aa, 89 kDa
• Poids moléculaire observé: 89 kDa
• Numéro d’acquisition GenBank: BC035077
• Symbole du gène: SMYD4
• Identification du gène (NCBI): 114826
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SMYD4, also named as SET and MYND domain-containing protein 4, is a 804 amino acid protein, which contains 1 MYND-type zinc finger and 1 SET domain. SMYD4 belongs to the class V-like SAM-binding methyltransferase superfamily. SMYD4, as a potential tumor suppressor, plays a critical role in breast carcinogenesis at least partly through inhibiting the expression of Pdgfr-alpha, and could be a novel target for improving treatment of breast cancer. SMYD4 is a muscle-specific transcriptional modulator involved in development.

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