Anticorps Monoclonal anti-SMYD4

SMYD4 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2F4B7

N° de cat : 66874-1-PBS

Synonymes

KIAA1936, SMYD4, ZMYND21

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Galerie de données de validation

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  WB analysis of MCF-7 using 66874-1-Ig (same clone as 66874-1-PBS)

  MCF-7 cells were subjected to SDS PAGE followed by western blot with 66874-1-Ig (SMYD4 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66874-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66874-1-PBS cible SMYD4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SMYD4 Protéine recombinante Ag11552
• Nom complet: SET and MYND domain containing 4
• Masse moléculaire calculée: 804 aa, 89 kDa
• Poids moléculaire observé: 85-89 kDa
• Numéro d’acquisition GenBank: BC035077
• Symbole du gène: SMYD4
• Identification du gène (NCBI): 114826
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SMYD4, also named as SET and MYND domain-containing protein 4, is a 804 amino acid protein, which contains 1 MYND-type zinc finger and 1 SET domain. SMYD4 belongs to the class V-like SAM-binding methyltransferase superfamily. SMYD4, as a potential tumor suppressor, plays a critical role in breast carcinogenesis at least partly through inhibiting the expression of Pdgfr-alpha, and could be a novel target for improving treatment of breast cancer. SMYD4 is a muscle-specific transcriptional modulator involved in development.

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