Anticorps Recombinant de lapin anti-SNAPIN

SNAPIN Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250300F4

N° de cat : 85949-1-PBS

Synonymes

Biogenesis of lysosome-related organelles complex 1 subunit 7, BLOC-1 subunit 7, BLOC1S7, SNAP associated protein, SNAP25BP

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Galerie de données de validation

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  WB analysis using 85949-1-RR (same clone as 85949-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85949-1-RR (SNAPIN antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85949-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85949-1-RR

  Biolayer interferometry (BLl) kinetic assays of 85949-1-RR against Human SNAPIN were performed. The affinity constant is 7.37 nM.

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Informations sur le produit

85949-1-PBS cible SNAPIN dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: SNAPIN Protéine recombinante Ag0101
• Nom complet: SNAP-associated protein
• Masse moléculaire calculée: 15 kDa
• Poids moléculaire observé: 15-18 kDa
• Numéro d’acquisition GenBank: BC000761
• Symbole du gène: SNAPIN
• Identification du gène (NCBI): 23557
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Snapin, a protein of relative molecular weight of 15kd, is implicated in neurotransmission by binding to SNAP-25. Snapin was enriched in neurons and exclusively located on synaptic vesicle membrane, which may be a PKA target for modulating transmitter release through the cAMP-dependent signal-transduction pathway. This anitbody can recognize the 15-18kd(Monomer) and 30-36kd(Dimer) forms of SNAPIN.

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