Anticorps Recombinant de lapin anti-SNAT2

SNAT2 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241059C6

N° de cat : 83968-5-PBS

Synonymes

SLC38A2, 241059C6, ATA2, KIAA1382, PRO1068

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Galerie de données de validation

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  WB analysis using 83968-5-RR (same clone as 83968-5-PBS)

  Boiled and unboiled mouse brain tissues were subjected to SDS PAGE followed by western blot with 83968-5-RR (SLC38A2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83968-5-PBS in a different storage buffer formulation.

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  IHC staining of mouse pancreas using 83968-5-RR (same clone as 83968-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 83968-5-RR (SNAT2 antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83968-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83968-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83968-5-RR against Human SNAT2 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83968-5-PBS cible SNAT2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: SNAT2 Protéine recombinante Ag23082
• Nom complet: solute carrier family 38, member 2
• Poids moléculaire observé: 56 kDa
• Numéro d’acquisition GenBank: BC040342
• Symbole du gène: SLC38A2
• Identification du gène (NCBI): 54407
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SNAT2 (Sodium-dependent neutral amino acid transporter-2), the ubiquitous member of SLC38 family, accounts for the activity of transport system A for neutral amino acids in most mammalian tissues (PMID: 16734764). SNAT2 mediates uptake of neutral α-amino acids and are expressed in central neurons (PMID: 19240036). SNAT2 is expressed in breast cancer cell lines. SLC38A2 also acts as a selective target for inhibiting growth of Gln-dependent breast cancer cell lines (PMID: 33028955).

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