Anticorps Polyclonal de lapin anti-SNF2L

SNF2L Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29461-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 29461-1-AP (same clone as 29461-1-PBS)

  U-87 MG cells were subjected to SDS PAGE followed by western blot with 29461-1-AP (SNF2L antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29461-1-PBS in a different storage buffer formulation.

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  WB analysis of U-251 using 29461-1-AP (same clone as 29461-1-PBS)

  U-251 cells were subjected to SDS PAGE followed by western blot with 29461-1-AP (SNF2L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29461-1-PBS in a different storage buffer formulation.

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  WB analysis of SH-SY5Y using 29461-1-AP (same clone as 29461-1-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 29461-1-AP (SNF2L antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29461-1-PBS in a different storage buffer formulation.

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  IHC staining of rat lung using 29461-1-AP (same clone as 29461-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat lung tissue slide using 29461-1-AP (SNF2L antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29461-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse lung using 29461-1-AP (same clone as 29461-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 29461-1-AP (SNF2L antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29461-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29461-1-PBS cible SNF2L dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SNF2L Protéine recombinante Ag30657
• Nom complet: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
• Masse moléculaire calculée: 123 kDa
• Poids moléculaire observé: 120-130 KDa
• Numéro d’acquisition GenBank: NM_003069
• Symbole du gène: SMARCA1/SNF2L
• Identification du gène (NCBI): 6594
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SNF2L, also named as SMARCA1, NURF140 and ISWI, encodes the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription (PMID: 28801535). SNF2L was shown to promote neurite outgrowth as well as regulate the human engrailed homeotic genes, important regulators of brain development (PMID: 15310751). The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells (PMID: 25462860). SNF2L has 2 isoforms with MW of 123 kDa and 121 kDa, and can be detected as 120-130 kDa.

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