Anticorps Polyclonal de lapin anti-SNIP/p140Cap

SNIP/p140Cap Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29890-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 29890-1-AP (same clone as 29890-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29890-1-AP (SNIP antibody) at dilution of 1:30000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29890-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29890-1-PBS cible SNIP/p140Cap dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SNIP/p140Cap Protéine recombinante Ag31857
• Nom complet: SNAP25-interacting protein
• Masse moléculaire calculée: 127 kDa
• Poids moléculaire observé: 145 kDa
• Symbole du gène: SNIP
• Identification du gène (NCBI): 80725
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SNIP, also named SRC kinase signaling inhibitor 1 (SRCIN1) and p140 Cas-associated protein (p140CAP), contains two regions of highly charged amino acids, two proline-rich regions, and two coiled-coil domains. SNIP plays a role in SRC inactivation and acts as a tumor suppressor gene in cancers. MiR-32 suppresses the expression of SNIP, thereby suppressing proliferation and epithelial-mesenchymal transition (EMT) of human liver cancer cells (PMID: 28550679).

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