Anticorps Polyclonal de lapin anti-SNRPD1

SNRPD1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10352-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of HEK-293 using 10352-1-AP (same clone as 10352-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 10352-1-AP (SNRPD1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10352-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 10352-1-AP (same clone as 10352-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 10352-1-AP (SNRPD1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10352-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HL-60 using 10352-1-AP (same clone as 10352-1-PBS)

  HL-60 cells were subjected to SDS PAGE followed by western blot with 10352-1-AP (SNRPD1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10352-1-PBS in a different storage buffer formulation.

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Informations sur le produit

10352-1-PBS cible SNRPD1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SNRPD1 Protéine recombinante Ag0364
• Nom complet: small nuclear ribonucleoprotein D1 polypeptide 16kDa
• Masse moléculaire calculée: 16 kDa
• Poids moléculaire observé: 13 kDa
• Numéro d’acquisition GenBank: BC001721
• Symbole du gène: SNRPD1
• Identification du gène (NCBI): 6632
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Systemic lupus erythematosus is characterized by antibodies to a variety of intracellular self-antigens, such as dsDNA and Sm, and these serve as hallmarks in the diagnosis of systemic autoimmune diseases. SNRPD1 is one Sm components of the small nuclear ribonucleoprotein complexes(snRNPs). It's a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA. This antibody detectes 13-16 kDa (SMD1) and 30 kDa (SMD1/SMD2 dimer form; PMID:15525645).

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