Anticorps Recombinant de lapin anti-SOD1

SOD1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240888B9

N° de cat : 83857-6-PBS

Synonymes

IPOA, hSod1, homodimer, EC:1.15.1.1, ALS1

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Galerie de données de validation

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  WB analysis using 83857-6-RR (same clone as 83857-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83857-6-RR (SOD1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83857-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83857-6-RR

  Biolayer interferometry (BLl) kinetic assays of 83857-6-RR against Human SOD1 were performed. The affinity constant is 13.0 nM.

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Informations sur le produit

83857-6-PBS cible SOD1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: superoxide dismutase 1, soluble
• Masse moléculaire calculée: 16kDa
• Poids moléculaire observé: 16-20 kDa
• Numéro d’acquisition GenBank: NM_000454.5
• Symbole du gène: SOD1
• Identification du gène (NCBI): 6647
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.

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