Anticorps Polyclonal de lapin anti-SON

SON Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28046-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of mouse colon using 28046-1-AP (same clone as 28046-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 28046-1-AP (SON antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28046-1-PBS in a different storage buffer formulation.

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  IHC staining of human thyroid cancer using 28046-1-AP (same clone as 28046-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 28046-1-AP (SON antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28046-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 28046-1-AP (same clone as 28046-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 28046-1-AP (SON antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28046-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28046-1-PBS cible SON dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SON Protéine recombinante Ag27620
• Nom complet: SON DNA binding protein
• Masse moléculaire calculée: 264 aa
• Numéro d’acquisition GenBank: NM_001291411
• Symbole du gène: SON
• Identification du gène (NCBI): 6651
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SON, also called C21orf50 and DBP5, is a nuclear speckle-localized protein that shares homology with pre-mRNA splicing accessory factors (PMID: 10950926). It is an RNA-binding protein that acts as an mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites, and specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG (PMID: 20581448; 21504830).

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