Anticorps Monoclonal anti-SORD

SORD Monoclonal Antibody for WB, ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

4A8E1

N° de cat : 67625-1-PBS

Synonymes

(R,R)-butanediol dehydrogenase, 4A8E1, EC:1.1.1.-, EC:1.1.1.14, EC:1.1.1.4

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Galerie de données de validation

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  WB analysis using 67625-1-Ig (same clone as 67625-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67625-1-Ig (SORD antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control. This data was developed using the same antibody clone with 67625-1-PBS in a different storage buffer formulation.

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  WB analysis of HSC-T6 using 67625-1-Ig (same clone as 67625-1-PBS)

  HSC-T6 cells were subjected to SDS PAGE followed by western blot with 67625-1-Ig (SORD antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67625-1-PBS in a different storage buffer formulation.

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  WB analysis of PC-12 using 67625-1-Ig (same clone as 67625-1-PBS)

  PC-12 cells were subjected to SDS PAGE followed by western blot with 67625-1-Ig (SORD antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67625-1-PBS in a different storage buffer formulation.

• 

  WB analysis of NIH/3T3 using 67625-1-Ig (same clone as 67625-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 67625-1-Ig (SORD antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67625-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67625-1-PBS cible SORD dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SORD Protéine recombinante Ag8651
• Nom complet: sorbitol dehydrogenase
• Masse moléculaire calculée: 357 aa, 38 kDa
• Poids moléculaire observé: 38 kDa
• Numéro d’acquisition GenBank: BC021085
• Symbole du gène: SORD
• Identification du gène (NCBI): 6652
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SORD(Sorbitol dehydrogenase) is also named as L-iditol 2-dehydrogenase and belongs to the zinc-containing alcohol dehydrogenase family. It catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. This protein can form a homotetramer(PMID:12962626). Measurement of SORD is a specific indicator of liver cell damage and parenchymal.

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