Anticorps Polyclonal de lapin anti-SOSTDC1

SOSTDC1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22213-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 22213-1-AP (same clone as 22213-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22213-1-AP (SOSTDC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22213-1-PBS in a different storage buffer formulation.

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  IF Staining of Saos-2 using 22213-1-AP (same clone as 22213-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed Saos-2 cells using SOSTDC1 antibody (22213-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 22213-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22213-1-PBS cible SOSTDC1 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SOSTDC1 Protéine recombinante Ag17538
• Nom complet: sclerostin domain containing 1
• Masse moléculaire calculée: 206 aa, 23 kDa
• Poids moléculaire observé: 23-26 kDa
• Numéro d’acquisition GenBank: BC008484
• Symbole du gène: SOSTDC1
• Identification du gène (NCBI): 25928
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SOSTDC1 (Sclerostin domain-containing protein 1), also known as Ectodin (Ectodermal BMP inhibitor), is a member of the sclerostin family. It is an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain and is highly abundant in milk and kidney. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.

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