Anticorps Polyclonal de lapin anti-SPAG11A/B

SPAG11A/B Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16770-1-PBS

Synonymes

SPAG11A, Antimicrobial-like protein Bin-1b, BIN1B, EP2, He2

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Galerie de données de validation

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  WB analysis of human testis using 16770-1-AP (same clone as 16770-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 16770-1-AP (SPAG11A/B antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16770-1-PBS in a different storage buffer formulation.

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  WB analysis of human brain using 16770-1-AP (same clone as 16770-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 16770-1-AP (SPAG11A/B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16770-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 16770-1-AP (same clone as 16770-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 16770-1-AP (SPAG11A/B antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 16770-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 16770-1-AP (same clone as 16770-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 16770-1-AP (SPAG11A/B antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 16770-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 16770-1-AP (same clone as 16770-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 16770-1-AP (SPAG11A/B antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 16770-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 16770-1-AP (same clone as 16770-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 16770-1-AP (SPAG11A/B antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 16770-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 16770-1-AP (same clone as 16770-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 16770-1-AP (SPAG11A/B antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 16770-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 16770-1-AP (same clone as 16770-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta using 16770-1-AP (SPAG11A/B antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 16770-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16770-1-PBS cible SPAG11A/B dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SPAG11A/B Protéine recombinante Ag9846
• Nom complet: sperm associated antigen 11A
• Masse moléculaire calculée: 123 aa, 14 kDa
• Poids moléculaire observé: 20 kDa
• Numéro d’acquisition GenBank: BC058833
• Symbole du gène: SPAG11A
• Identification du gène (NCBI): 653423
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Sperm binding proteins and their C-terminal peptides of the Sperm Associated Antigen 11 (SPAG11) family are found to play an important role in epididymal innate immunity in addition to their role in sperm maturation(PMID:16643671). SPAG11 peptides resulting due to cleavage at the furin-like proprotein convertase motif are reported in the epididymal fluid, ejaculate and on sperm and their antimicrobial activity demonstrated.SPAG11A belongs to this family and is also named as EP2,HE2. It has 4 isoforms produced by alternative splicing. This antibody recognizes SPAG11A and SPAG11B, but not SPAG11, because SPAG11 is a different transcript.

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