Anticorps Polyclonal de lapin anti-SPDYC

SPDYC Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22471-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human liver using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22471-1-PBS cible SPDYC dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SPDYC Protéine recombinante Ag18126
• Nom complet: speedy homolog C (Xenopus laevis)
• Masse moléculaire calculée: 293 aa, 33 kDa
• Poids moléculaire observé: 33-40 kDa
• Numéro d’acquisition GenBank: BC137244
• Symbole du gène: SPDYC
• Identification du gène (NCBI): 387778
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SPDYC(Speedy protein C), also known as RINGOC and Ringo2, promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Downregulation of SPDYC inhibits cell growth, reduces the fraction of cells in G1, and increases the S and G2 populations(PMID: 18802405). SPDYC is involved in the spindle-assembly checkpoint and required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores(Uniprot).

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