Anticorps Recombinant de lapin anti-SPHK1

SPHK1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241017A6

N° de cat : 84640-1-PBS

Synonymes

241017A6, Acetyltransferase SPHK1, EC:2.3.1.-, EC:2.7.1.91, SK1

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Galerie de données de validation

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  WB analysis of THP-1 using 84640-1-RR (same clone as 84640-1-PBS)

  THP-1 cells were subjected to SDS PAGE followed by western blot with 84640-1-RR (SPHK1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84640-1-PBS in a different storage buffer formulation.

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Informations sur le produit

84640-1-PBS cible SPHK1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: sphingosine kinase 1
• Masse moléculaire calculée: 51 kDa
• Poids moléculaire observé: 42 kDa
• Numéro d’acquisition GenBank: NM_182965
• Symbole du gène: SPHK1
• Identification du gène (NCBI): 8877
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SPHK(Sphingosine kinase 1) is also named as SPHK, SPK.It catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions and is precariously perched at the balance point between progrowth and pro-death signalling in the cell.Endogenous SPHK1 purified from placenta has identical enzymatic characteristics, suggesting posttranslational modification does not effect functional properties(PMID:10947957).It has 2 isoforms produced by alternative splicing and can form the oligomeric structure(PMID:22335554).

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