Anticorps Polyclonal de lapin anti-SPIRE1

SPIRE1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11295-1-PBS

Synonymes

KIAA1135, Protein spire homolog 1, Spir 1, SPIR1, Spir-1

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Galerie de données de validation

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  WB analysis using 11295-1-AP (same clone as 11295-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11295-1-AP (SPIRE1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11295-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 11295-1-AP (same clone as 11295-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11295-1-AP (SPIRE1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with . This data was developed using the same antibody clone with 11295-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 11295-1-AP (same clone as 11295-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11295-1-AP (SPIRE1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with . This data was developed using the same antibody clone with 11295-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse stomach using 11295-1-AP (same clone as 11295-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 11295-1-AP (SPIRE1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11295-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11295-1-PBS cible SPIRE1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SPIRE1 Protéine recombinante Ag1798
• Nom complet: spire homolog 1 (Drosophila)
• Masse moléculaire calculée: 64 kDa
• Poids moléculaire observé: 50-60 kDa, 95 kDa
• Numéro d’acquisition GenBank: BC016825
• Symbole du gène: SPIRE1
• Identification du gène (NCBI): 56907
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SPIRE1, Protein spire homolog 1, belongs to the family of Wiskott-Aldrich homology region-2 (WH2) proteins (PMID: 11747823). SPIRE1 acts as an actin nucleation factor, associated with the slow-growing pointed end of the new filament (PMID: 11747823, PMID: 21620703). SPIRE1 and FMN2 promote assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (PMID: 26287480).

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