Anticorps Polyclonal de lapin anti-SPOPL

SPOPL Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17740-1-PBS

Synonymes

HIB homolog 2, Roadkill homolog 2, speckle type POZ protein like, Speckle-type POZ protein-like

---

Galerie de données de validation

• 

  WB analysis using 17740-1-AP (same clone as 17740-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17740-1-AP (SPOPL antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17740-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

17740-1-PBS cible SPOPL dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SPOPL Protéine recombinante Ag11951
• Nom complet: speckle-type POZ protein-like
• Masse moléculaire calculée: 392 aa, 45 kDa
• Poids moléculaire observé: 39-45 kDa
• Numéro d’acquisition GenBank: BC071613
• Symbole du gène: SPOPL
• Identification du gène (NCBI): 339745
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Speckle Type POZ Protein Like (SPOPL), a member of the MATH-BTB protein family, was frst identifed in 2010 with 82.6% sequence homology with Speckle-type POZ protein (SPOP). SPOPL is an E3 ubiquitin ligase protein that ubiquitinates and degrades the target protein. SPOPL can be used as a potential prognostic biomarker for glioblastoma multiforme in clinical work and promotes the proliferation and stemness of glioma stem cells by activating the Notch signaling pathway (PMID:37523046).

{{ptg:RelatedPrimaryAntibodies}}