Anticorps Polyclonal de lapin anti-SPPL2A

SPPL2A Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13255-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of human colon using 13255-1-AP (same clone as 13255-1-PBS)

  human colon tissue were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  WB analysis of Jurkat using 13255-1-AP (same clone as 13255-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  WB analysis of Jurkat using 13255-1-AP (same clone as 13255-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse colon using 13255-1-AP (same clone as 13255-1-PBS)

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human colon using 13255-1-AP (same clone as 13255-1-PBS)

  human colon tissue were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13255-1-PBS cible SPPL2A dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SPPL2A Protéine recombinante Ag3935
• Nom complet: signal peptide peptidase-like 2A
• Masse moléculaire calculée: 520 aa, 58 kDa
• Poids moléculaire observé: 58 kDa
• Numéro d’acquisition GenBank: BC025740
• Symbole du gène: SPPL2A
• Identification du gène (NCBI): 84888
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SPPL2A(Signal peptide peptidase-like 2A) is also named as IMP3(Intramembrane protease 3), PSL2(Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A (SPPL2a) is localised in lysosomes/late endosomes(PMID:21896273). This protein has a signal peptide with 25 amino acid and seven glycosylation sites.

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