Anticorps Monoclonal anti-SPTBN1

SPTBN1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, Lapin, porc, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1E1D1

N° de cat : 67978-1-PBS

Synonymes

Beta II spectrin, betaSpII, ELF, Fodrin beta chain, Spectrin beta chain, brain 1, SPTB2, SPTBN1

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Galerie de données de validation

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  WB analysis using 67978-1-Ig (same clone as 67978-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67978-1-Ig (SPTBN1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67978-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse cerebellum using 67978-1-Ig (same clone as 67978-1-PBS)

  mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 67978-1-Ig (SPTBN1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67978-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 67978-1-Ig (same clone as 67978-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67978-1-Ig (SPTBN1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67978-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67978-1-PBS cible SPTBN1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris

• Réactivité: Humain, Lapin, porc, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SPTBN1 Protéine recombinante Ag31713
• Nom complet: spectrin, beta, non-erythrocytic 1
• Masse moléculaire calculée: 2364 aa, 275 kDa
• Poids moléculaire observé: 250-275 kDa
• Numéro d’acquisition GenBank: BC137282
• Symbole du gène: SPTBN1
• Identification du gène (NCBI): 6711
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SPTBN1 is the non-erythrocytic form of β-spectrin or β-fodrin. Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. Reduced expression of SPTBN1 has been found to correlate with shorter survival of patients with hepatocellular cancer, pancreatic cancer and other malignancies of the gastrointestinal tract, suggesting tumor suppression ability of this protein.

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