Anticorps Monoclonal anti-SPTLC2

• Phare
• Validé par KD/KO

SPTLC2 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2G6A12

N° de cat : 68094-1-PBS

Synonymes

KIAA0526, LCB 2, LCB2, LCB2a, Serine palmitoyltransferase 2, SPT 2, SPT2, SPTLC2

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Galerie de données de validation

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  WB analysis using 68094-1-Ig (same clone as 68094-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68094-1-Ig (SPTLC2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Beta Actin Monoclonal antibody (HRP-66009) as loading control. This data was developed using the same antibody clone with 68094-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 68094-1-Ig (same clone as 68094-1-PBS)

  WB result of SPTLC2 antibody (68094-1-Ig; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SPTLC2 transfected HEK-293 cells. This data was developed using the same antibody clone with 68094-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68094-1-PBS cible SPTLC2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SPTLC2 Protéine recombinante Ag28380
• Nom complet: serine palmitoyltransferase, long chain base subunit 2
• Masse moléculaire calculée: 63 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC005123
• Symbole du gène: SPTLC2
• Identification du gène (NCBI): 9517
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Serine palmitoyltransferase long chain base subunit 2 (SPTLC2) is one of the subunits of the heterodimeric molecule Serine palmitoyltransferase (SPT). Sptlc2 deficiency not only affected T cell sphingolipid anabolism but also led to prolonged activation of the mechanistic target of rapamycin complex 1 (PMID: 30952607).

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