Anticorps Polyclonal de lapin anti-ST3GAL6

• Phare
• Validé par KD/KO

ST3GAL6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13154-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 13154-1-AP (same clone as 13154-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13154-1-AP (ST3GAL6 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13154-1-PBS in a different storage buffer formulation.

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  WB analysis of human heart using 13154-1-AP (same clone as 13154-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 13154-1-AP (ST3GAL6 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13154-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 13154-1-AP (same clone as 13154-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 13154-1-AP (ST3GAL6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13154-1-PBS in a different storage buffer formulation.

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  IHC staining of human urothelial carcinoma using 13154-1-AP (same clone as 13154-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 13154-1-AP (ST3GAL6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13154-1-PBS in a different storage buffer formulation.

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  IHC staining of human urothelial carcinoma using 13154-1-AP (same clone as 13154-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 13154-1-AP (ST3GAL6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13154-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 13154-1-AP (same clone as 13154-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 13154-1-AP (ST3GAL6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13154-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13154-1-PBS cible ST3GAL6 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ST3GAL6 Protéine recombinante Ag3782
• Nom complet: ST3 beta-galactoside alpha-2,3-sialyltransferase 6
• Masse moléculaire calculée: 331 aa, 38 kDa
• Poids moléculaire observé: 50-60 kDa
• Numéro d’acquisition GenBank: BC023312
• Symbole du gène: ST3GAL6
• Identification du gène (NCBI): 10402
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ST3GAL6, also named as SIAT10, belongs to the glycosyltransferase 29 family. ST3GAL6 is involved in the synthesis of sialyl-paragloboside, which is a precursor of sialyl-Lewis X determinant. ST3GAL6 has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. ST3GAL6 is known to promote cell adhesion and migration of multiple myeloma cells by increasing the synthesis of selectin ligands. ST3GAL6 has 2 isoforms with the molecular mass of 25 and 38 kDa. Sometimes higher molecular weight about 50-60 kDa can also be observed, which may be a glycosylated modified variant of ST3GAL6. (PMID: 31914669, 30220088)

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