Anticorps Monoclonal anti-STAM

STAM Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1F5C2

N° de cat : 68628-1-PBS

Synonymes

DKFZp686J2352, STAM, STAM 1, STAM1

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Galerie de données de validation

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  WB analysis using 68628-1-Ig (same clone as 68628-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68628-1-Ig (STAM antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 68628-1-PBS in a different storage buffer formulation.

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  WB analysis of RAW 264.7 using 68628-1-Ig (same clone as 68628-1-PBS)

  RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 68628-1-Ig (STAM antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68628-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68628-1-PBS cible STAM dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: STAM Protéine recombinante Ag33192
• Nom complet: signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
• Masse moléculaire calculée: 59 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC030586
• Symbole du gène: STAM
• Identification du gène (NCBI): 8027
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

STAM, also named as STAM1, belongs to the STAM family. It is involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. STAM may also play a role in T-cell development. It is involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs). Together with HRS, STAM forms ESCRT-0. STAM was originally identified as an adaptor protein involved in cytokine signaling.(PMID:20505072)

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