Anticorps Polyclonal de lapin anti-STK11/LKB1

• Phare
• Validé par KD/KO

STK11/LKB1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29323-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 29323-1-AP (same clone as 29323-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29323-1-AP (STK11 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  WB analysis of MCF-7 using 29323-1-AP (same clone as 29323-1-PBS)

  WB result of STK11/LKB1 antibody (29323-1-AP; 1:8000; incubated at room temperature for 1.5 hours) with sh-Control and sh-STK11/LKB1 transfected MCF-7 cells. This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  WB analysis of A431 using 29323-1-AP (same clone as 29323-1-PBS)

  WB result of STK11/LKB1 antibody (29323-1-AP; 1:8000; incubated at room temperature for 1.5 hours) with sh-Control and sh-STK11/LKB1 transfected A431 cells. This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 29323-1-AP (same clone as 29323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 29323-1-AP (STK11/LKB1 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 29323-1-AP (same clone as 29323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 29323-1-AP (STK11/LKB1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 29323-1-AP (same clone as 29323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 29323-1-AP (STK11/LKB1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse testis using 29323-1-AP (same clone as 29323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 29323-1-AP (STK11/LKB1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse testis using 29323-1-AP (same clone as 29323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 29323-1-AP (STK11/LKB1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lymphoma using 29323-1-AP (same clone as 29323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 29323-1-AP (STK11/LKB1 antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lymphoma using 29323-1-AP (same clone as 29323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 29323-1-AP (STK11/LKB1 antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 29323-1-AP (same clone as 29323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 29323-1-AP (STK11/LKB1 antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29323-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

29323-1-PBS cible STK11/LKB1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: STK11/LKB1 Protéine recombinante Ag30903
• Nom complet: serine/threonine kinase 11
• Masse moléculaire calculée: 49 kDa
• Poids moléculaire observé: 50-55 kDa
• Numéro d’acquisition GenBank: BC007981
• Symbole du gène: LKB1
• Identification du gène (NCBI): 6794
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

STK11(serine/threonine-protein kinase 11) is also named as LKB1, PJS, and belongs to the protein kinase superfamily. It controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. The tumour suppressor protein LKB1 is a serine/threonine kinase that has been causally linked to Peutz-Jeghers syndrome (PJS). Defects in STK11 are a cause of Peutz-Jeghers syndrome (PJS) and defects in STK11 have been associated with testicular germ cell tumor (TGCT) and some sporadic cancers, especially lung cancers. STK11 has 2 isoforms with MW of 49 kDa and 45 kDa, and can be detected as 50-54 kDa after posttranslational modification.

{{ptg:RelatedPrimaryAntibodies}}