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Anticorps Polyclonal de lapin anti-STK39

STK39 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31064-1-PBS

Synonymes

DCHT, PASK, SPAK, Ste 20 related kinase

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using STK39 Polyclonal antibody (31064-1-AP)

    WB analysis using 31064-1-AP (same clone as 31064-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31064-1-AP (STK39 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31064-1-PBS in a different storage buffer formulation.

Informations sur le produit

31064-1-PBS cible STK39 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène STK39 Protéine recombinante Ag34503
Nom complet serine threonine kinase 39 (STE20/SPS1 homolog, yeast)
Masse moléculaire calculée59 kDa
Poids moléculaire observé68 kDa
Numéro d’acquisition GenBankBC166614
Symbole du gène STK39
Identification du gène (NCBI) 27347
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

STK39 (Serine/Threonine Kinase 39) is a proline- and alanine-rich Ste20-related kinase (also named as SPAK), which is composed of a short N-terminal proline and alanine repeats (PAPA box), a kinase catalytic domain and a C-terminal regulatory domain (PMID: 16382158). In mammalians, STK39 plays an important role in ion homeostasis by regulating the cation chloride cotransporters' activities, which is crucial for the modulation of renal salt transport and blood pressure (PMID: 33500714). Notably, STK39 is also implicated in the regulation of tumor cell proliferation, migration, and invasion in multiple cancers, including osteosarcoma and cervical cancer (PMID: 34335956).

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