Anticorps Monoclonal anti-STRA8

STRA8 Monoclonal Antibody for WB, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, Lapin, souris

Applications

WB, IF, ELISA

Conjugaison

Non conjugué

Publications

2

CloneNo.

1D7E3

N° de cat : 68071-1-Ig

Synonymes

STRA8

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Galerie de données de validation

• 

  WB analysis of human testis using 68071-1-Ig

  human testis tissue were subjected to SDS PAGE followed by western blot with 68071-1-Ig (STRA8 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of rabbit testis using 68071-1-Ig

  rabbit testis tissue were subjected to SDS PAGE followed by western blot with 68071-1-Ig (STRA8 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of mouse testis using 68071-1-Ig

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 68071-1-Ig (STRA8 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu testiculaire humain, tissu testiculaire de lapin, tissu testiculaire de souris

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below
• IF: See 1 publications below

Informations sur le produit

68071-1-Ig cible STRA8 dans les applications de WB, IF, ELISA et montre une réactivité avec des échantillons Humain, Lapin, souris

• Réactivité: Humain, Lapin, souris
• Réactivité citée: souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: STRA8 Protéine recombinante Ag29680
• Nom complet: stimulated by retinoic acid gene 8 homolog (mouse)
• Masse moléculaire calculée: 37 kDa
• Poids moléculaire observé: 43-60 kda
• Numéro d’acquisition GenBank: NM_182489
• Symbole du gène: STRA8
• Identification du gène (NCBI): 346673
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
• Conditions de stockage: Stocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Stimulated by retinoic acid 8 (Stra8), one of genes induced by retinoic acid (RA), is required for the meiotic initiation of male spermatogenesis. Stimulated by Retinoic Acid Gene 8 (STRA8) protein has been proposed as the molecular effector of Retinoic Acid (RA) involved in meiosis-inductive activity. Stra8 is a 45-kDa vertebrate-specific gene, without significant homologous proteins, expressed in the cytoplasm and nuclei of germ cells between mitosis and meiosis and presents exclusively in the embryonic and postnatal gonads of mammals. (PMID: 30106128, PMID: 31253359)

Publications

Species	Application	Title
mouse	WB,IF	Environ Pollut; Wnt10a downregulation contributes to MEHP-induced disruption of self-renewal and differentiation balance and proliferation inhibition in GC-1 cells: Insights from multiple transcriptomic profiling; Authors - Yifan Hong
mouse	WB	J Hazard Mater; Prenatal and postnatal exposure to polystyrene microplastics induces testis developmental disorder and affects male fertility in mice; Authors - Tianxin Zhao