Anticorps Recombinant de lapin anti-STRN

STRN Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242532D8

N° de cat : 85058-4-PBS

Synonymes

242532D8, SG2NA, Striatin

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Galerie de données de validation

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  WB analysis using 85058-4-RR (same clone as 85058-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85058-4-RR (STRN antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85058-4-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 85058-4-RR (same clone as 85058-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 85058-4-RR (STRN antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85058-4-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 85058-4-RR (same clone as 85058-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 85058-4-RR (STRN antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85058-4-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 85058-4-RR (same clone as 85058-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using STRN antibody (85058-4-RR, Clone: 242532D8 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85058-4-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 85058-4-RR (same clone as 85058-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using STRN antibody (85058-4-RR, Clone: 242532D8 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85058-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85058-4-RR

  Biolayer interferometry (BLl) kinetic assays of 85058-4-RR against Human STRN were performed. The affinity constant is 0.433 nM.

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Informations sur le produit

85058-4-PBS cible STRN dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: STRN Protéine recombinante Ag15984
• Nom complet: striatin, calmodulin binding protein
• Masse moléculaire calculée: 780 aa, 86 kDa
• Poids moléculaire observé: 110 kDa
• Numéro d’acquisition GenBank: BC106879
• Symbole du gène: STRN
• Identification du gène (NCBI): 6801
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

STRN (Striatin), a 780-amino acid protein, was identified and cloned more than a decade ago. In adult mammals, striatin is mainly expressed in neurons of both the central and peripheral nervous systems with very high levels of expression in the striatum, hence its name. STRN-ALK fusion may be a potential therapeutic target in the aggressive forms of thyroid cancer (PMID: 24475247).

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