Anticorps Monoclonal anti-STXBP2

STXBP2 Monoclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, souris

Applications

WB, IHC, IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3G3A12

N° de cat : 66238-1-PBS

Synonymes

3G3A12, Hunc18b, MUNC18 2, Munc18-2, pp10122

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Galerie de données de validation

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  WB analysis using 66238-1-Ig (same clone as 66238-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66238-1-Ig (STXBP2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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  WB analysis of fetal human brain using 66238-1-Ig (same clone as 66238-1-PBS)

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66238-1-Ig (STXBP2 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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  IP experiment of K-562 using 66238-1-Ig (same clone as 66238-1-PBS)

  IP result of anti-STXBP2 (IP:66238-1-Ig, 5ug; Detection:66238-1-Ig 1:2000) with K-562 cells lysate 3200ug. This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 66238-1-Ig (same clone as 66238-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66238-1-Ig (STXBP2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 66238-1-Ig (same clone as 66238-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66238-1-Ig (STXBP2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 66238-1-Ig (same clone as 66238-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66238-1-Ig (STXBP2 antibody) at dilution of 1:1000 (under 4x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 66238-1-Ig (same clone as 66238-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66238-1-Ig (STXBP2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 66238-1-Ig (same clone as 66238-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 66238-1-Ig (STXBP2 Antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 66238-1-Ig (same clone as 66238-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 66238-1-Ig (STXBP2 Antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 66238-1-Ig (same clone as 66238-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using STXBP2 antibody (66238-1-Ig, Clone: 3G3A12 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 66238-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66238-1-PBS cible STXBP2 dans les applications de WB, IHC, IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: STXBP2 Protéine recombinante Ag7640
• Nom complet: syntaxin binding protein 2
• Masse moléculaire calculée: 593 aa, 66 kDa
• Poids moléculaire observé: 66 kDa
• Numéro d’acquisition GenBank: BC002869
• Symbole du gène: STXBP2
• Identification du gène (NCBI): 6813
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Syntaxin-binding protein 2 (STXBP2, also known as Unc18-2) belongs to the STXBP/unc-18/SEC1 family. STXBP2 is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in the STXBP2 gene are associated with familial hemophagocytic lymphohistiocytosis.

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