Anticorps Polyclonal de lapin anti-SUR2/ABCC9

SUR2/ABCC9 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13599-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 13599-1-AP (same clone as 13599-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13599-1-AP (SUR2/ABCC9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13599-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 13599-1-AP (same clone as 13599-1-PBS)

  mouse heart were subjected to SDS PAGE followed by western blot with 13599-1-AP (SUR2/ABCC9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13599-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13599-1-PBS cible SUR2/ABCC9 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SUR2/ABCC9 Protéine recombinante Ag4536
• Nom complet: ATP-binding cassette, sub-family C (CFTR/MRP), member 9
• Masse moléculaire calculée: 1549 aa, 174 kDa
• Poids moléculaire observé: 174 kDa
• Numéro d’acquisition GenBank: BC033804
• Symbole du gène: SUR2/ABCC9
• Identification du gène (NCBI): 10060
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ABCC9, also known as SUR2, belongs to the ABC transporter superfamily. ABCC9 is a subunit of ATP-sensitive potassium channels (KATP), forming cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (PMID: 9831708). ABCC9 is thought to form ATP-sensitive potassium channels in cardiac, skeletal, vascular, and non-vascular smooth muscle. Defects in ABCC9 cause dilated cardiomyopathy 10 and familial atrial fibrillation type 12 (ATFB12)(PMID: 15034580,17245405).

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