Anticorps Recombinant de lapin anti-SYN1-Specific

SYN1-Specific Recombinant Antibody for WB, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242415H5

N° de cat : 85360-1-PBS

Synonymes

SYN1, Synapsin I, 242415H5, Brain protein 4.1, SYN1a

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Galerie de données de validation

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  WB analysis using 85360-1-RR (same clone as 85360-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85360-1-RR (SYN1-Specific antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85360-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse retina using 85360-1-RR (same clone as 85360-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse retina tissue using SYN1-Specific antibody (85360-1-RR, Clone: 242415H5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85360-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85360-1-PBS cible SYN1-Specific dans les applications de WB, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: synapsin I
• Masse moléculaire calculée: 74 kDa
• Poids moléculaire observé: 70-80 kDa
• Numéro d’acquisition GenBank: NM_006950
• Symbole du gène: SYN1
• Identification du gène (NCBI): 6853
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SYN1, also named Brain protein 4.1, belongs to the synapsin family. SYN1 is a neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level. Defects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders (XELBD).

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