Anticorps Monoclonal anti-SYNGR1

SYNGR1 Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, Lapin, porc, rat, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2H2H1

N° de cat : 68176-1-PBS

Synonymes

Synaptogyrin-1, synaptogyrin 1, 2H2H1

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Galerie de données de validation

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  WB analysis using 68176-1-Ig (same clone as 68176-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68176-1-Ig (SYNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68176-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse retina using 68176-1-Ig (same clone as 68176-1-PBS)

  mouse retina tissue were subjected to SDS PAGE followed by western blot with 68176-1-Ig (SYNGR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68176-1-PBS in a different storage buffer formulation.

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  IHC staining of rat brain using 68176-1-Ig (same clone as 68176-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 68176-1-Ig (SYNGR1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68176-1-PBS in a different storage buffer formulation.

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  IHC staining of rat brain using 68176-1-Ig (same clone as 68176-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 68176-1-Ig (SYNGR1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68176-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 68176-1-Ig (same clone as 68176-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using SYNGR1 antibody (68176-1-Ig, Clone: 2H2H1 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68176-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68176-1-PBS cible SYNGR1 dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc, rat, souris

• Réactivité: Humain, Lapin, porc, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SYNGR1 Protéine recombinante Ag31309
• Nom complet: synaptogyrin 1
• Masse moléculaire calculée: 25 kDa
• Poids moléculaire observé: 29 kDa
• Numéro d’acquisition GenBank: BC000731
• Symbole du gène: SYNGR1
• Identification du gène (NCBI): 9145
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Synaptogyrins are one of the most abundant vesicle components and are involved in the regulation of neurotransmitter release and synaptic plasticity. Synaptogyrins comprise a family of tyrosine-phosphorylated proteins with three isoforms: two neuronal forms (synaptogyrin-1 and -3) and one ubiquitous form (synaptogyrin-2). The synaptogyrin 1 (SYNGR1) can act as a regulator of Ca2+-dependent exocytosis. SYNGR1 protein mutations are associated with schizophrenia and are considered to be positional candidate genes for schizophrenia.(PMID: 10383386; 10595519; 14755516; 14732601; 17049558)

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