Anticorps Polyclonal de lapin anti-SYT2

SYT2 Polyclonal Antibody for WB, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21245-1-PBS

Synonymes

Synaptotagmin II, Synaptotagmin-2, SytII

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Galerie de données de validation

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  WB analysis using 21245-1-AP (same clone as 21245-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21245-1-AP (SYT2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

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  WB analysis using 21245-1-AP (same clone as 21245-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21245-1-AP (SYT2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse cerebellum using 21245-1-AP (same clone as 21245-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse cerebellum tissue using SYT2 antibody (21245-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse cerebellum using 21245-1-AP (same clone as 21245-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse cerebellum tissue using SYT2 antibody (21245-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21245-1-PBS cible SYT2 dans les applications de WB, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SYT2 Protéine recombinante Ag15744
• Nom complet: synaptotagmin II
• Masse moléculaire calculée: 419 aa, 47 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC100815
• Symbole du gène: SYT2
• Identification du gène (NCBI): 127833
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SYT2 (Synaptotagmin-2) a synaptic vesicle membrane protein, functions as a calcium sensor in vesicular trafficking and exocytosis. SYT2 is also plays a role in dendrite formation by melanocytes (PMID: 23999003). Mutations in SYT2 are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. SYT2 mutations cause a complex presynaptic congenital myasthenic syndrome (PMID: 26519543).

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