Anticorps Recombinant de lapin anti-SYTL4

SYTL4 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

240556E2

N° de cat : 83564-5-PBS

Synonymes

synaptotagmin like 4, SLP4, Granuphilin, Exophilin-2, Exophilin 2

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Galerie de données de validation

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  WB analysis using 83564-5-RR (same clone as 83564-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83564-5-RR (SYTL4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83564-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83564-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83564-5-RR against Human SYTL4 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83564-5-PBS cible SYTL4 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: SYTL4 Protéine recombinante Ag2772
• Nom complet: synaptotagmin-like 4
• Masse moléculaire calculée: 671 aa, 76 kDa
• Poids moléculaire observé: 74-76 kDa
• Numéro d’acquisition GenBank: BC014913
• Symbole du gène: SYTL4
• Identification du gène (NCBI): 94121
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SYTL4, also known as SLP4 or granuphilin, is a member of the synaptotagmin-like protein (Slp) family. Members of this family are characterized by presence of an N-terminal Slp homology domain (SHD), which functions as a Rab27-binding domain, and C-terminal tandem C2 domains, putative Ca(2+)-binding motifs. SYTL4 is specifically expressed on dense-core granules in certain neuroendocrine cells and negatively controls dense-core vesicle exocytosis through specific interaction with Rab27A. (PMID: 16481396; 16473610)

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