Anticorps Recombinant de lapin anti-Selenoprotein P

Selenoprotein P Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242510E7

N° de cat : 85017-4-PBS

Synonymes

SEPP1, 242510E7

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Galerie de données de validation

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  WB analysis of human milk using 85017-4-RR (same clone as 85017-4-PBS)

  human milk were subjected to SDS PAGE followed by western blot with 85017-4-RR (Selenoprotein P antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85017-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85017-4-RR

  Biolayer interferometry (BLl) kinetic assays of 85017-4-RR against Human Selenoprotein P were performed. The affinity constant is 0.587 nM.

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Informations sur le produit

85017-4-PBS cible Selenoprotein P dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Selenoprotein P Protéine recombinante Ag32952
• Nom complet: selenoprotein P, plasma, 1
• Masse moléculaire calculée: 43 kDa
• Poids moléculaire observé: 45-60 kDa
• Numéro d’acquisition GenBank: NM_001085486.2
• Symbole du gène: Selenoprotein P
• Identification du gène (NCBI): 6414
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Selenoprotein P, also known as SEPP1, is expressed in the liver and heart and secreted into the plasma(PMID: 8421687). Selenoprotein P is implicated as an extracellular antioxidant involved in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2) and provides selenium to tissues such as brain and testis. In humans, it exists in plasma as two isoforms of approximately 50 and 60 kDa(PMID:19453253). Selenoprotein P is a glycosylated protein and deglycosylation of SEPP1 results in 45 kDa and 35 kDa isoforms(PMID: 25298198).

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