Anticorps Recombinant de lapin anti-Serpinc1

Serpinc1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250597D2

N° de cat : 86029-1-PBS

Synonymes

Antithrombin-III, At3, ATIII, Serpin C1

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Galerie de données de validation

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  WB analysis using 86029-1-RR (same clone as 86029-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86029-1-RR (Serpinc1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86029-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86029-1-PBS cible Serpinc1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Serpinc1 Protéine recombinante Eg2949
• Nom complet: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
• Masse moléculaire calculée: 52 kDa
• Poids moléculaire observé: 52 kDa
• Numéro d’acquisition GenBank: NM_080844.4
• Symbole du gène: Serpinc1
• Identification du gène (NCBI): 11905
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SERPINC1 is a gene encoding antithrombin, also known as antithrombin III. The main function of antithrombin is to inhibit coagulation proteases such as thrombin and factor Xa, thereby preventing excessive coagulation and maintaining normal hemostasis and blood flow. Mutations in the SERPINC1 gene can lead to antithrombin deficiency (ATD), which is an autosomal dominant genetic disorder. The expression profile/molecular weight observed is consistent with what has been described in the literature (PMID: 3609301, PMID: 25485983, PMID: 35935621).

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