Anticorps Polyclonal de lapin anti-Synaptotagmin-14

Synaptotagmin-14 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20561-1-PBS

Synonymes

Synaptotagmin XIV, SYT14, SytXIV

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Galerie de données de validation

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  WB analysis using 20561-1-AP (same clone as 20561-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20561-1-AP (Synaptotagmin-14 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20561-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 20561-1-AP (same clone as 20561-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 20561-1-AP (Synaptotagmin-14 antibody) at dilution of 1:300 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20561-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 20561-1-AP (same clone as 20561-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 20561-1-AP (Synaptotagmin-14 antibody) at dilution of 1:300 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20561-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20561-1-PBS cible Synaptotagmin-14 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: synaptotagmin XIV
• Masse moléculaire calculée: 62 kDa
• Poids moléculaire observé: 62-65 kDa
• Numéro d’acquisition GenBank: NM_153262
• Symbole du gène: Synaptotagmin-14
• Identification du gène (NCBI): 255928
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (PMID: 8058779). Synaptotagmin-14 (SYT14) is highly expressed in brain tissues. A homozygous mutation of SYT14 is involved in the pathogenesis of spinocerebellar ataxia (SCA) (PMID: 21835308).

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