Anticorps Monoclonal anti-Syntenin-1

Syntenin-1 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2B1A9

N° de cat : 68096-1-PBS

Synonymes

MDA 9, MDA9, Scaffold protein Pbp1, SDCBP, ST1, SYCL, Syndecan binding protein 1, Syntenin 1, TACIP18

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Galerie de données de validation

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  WB analysis using 68096-1-Ig (same clone as 68096-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68096-1-Ig (SDCBP antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68096-1-PBS in a different storage buffer formulation.

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  WB analysis of U2OS using 68096-1-Ig (same clone as 68096-1-PBS)

  U2OS cells were subjected to SDS PAGE followed by western blot with 68096-1-Ig (SDCBP antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68096-1-PBS in a different storage buffer formulation.

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  IHC staining of human malignant melanoma using 68096-1-Ig (same clone as 68096-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human malignant melanoma tissue slide using 68096-1-Ig (Syntenin-1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68096-1-PBS in a different storage buffer formulation.

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  IHC staining of human malignant melanoma using 68096-1-Ig (same clone as 68096-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human malignant melanoma tissue slide using 68096-1-Ig (Syntenin-1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68096-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68096-1-PBS cible Syntenin-1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Syntenin-1 Protéine recombinante Ag18078
• Nom complet: syndecan binding protein (syntenin)
• Masse moléculaire calculée: 298 aa, 32 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC113674
• Symbole du gène: Syntenin-1
• Identification du gène (NCBI): 6386
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Syntenin-1, also known as SDCBP (syndecan binding protein) and MDA-9 (melanoma differentiation-associated protein 9), was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. Syntenin-1 is a PDZ-domain-containing molecule that has many interaction partners, and regulates transmembrane-receptor trafficking, cell adhesion, tumor-cell metastasis and neuronal-synapse function. Syntenin-1 is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.

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