Anticorps Recombinant de lapin anti-TNFRSF13B/CD267

TNFRSF13B/CD267 Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250265D1

N° de cat : 85902-1-PBS

Synonymes

CD267, Taci, Tnfrsf13b, Transmembrane activator and CAML interactor, Tumor necrosis factor receptor superfamily member 13B

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Galerie de données de validation

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  WB analysis using 85902-1-RR (same clone as 85902-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85902-1-RR (TNFRSF13B/CD267 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85902-1-PBS in a different storage buffer formulation.

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  IF Staining of A20 using 85902-1-RR (same clone as 85902-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A20 cells using TNFRSF13B/CD267 antibody (85902-1-RR, Clone: 250265D1 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85902-1-PBS in a different storage buffer formulation.

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Informations sur le produit

85902-1-PBS cible TNFRSF13B/CD267 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TNFRSF13B/CD267 Protéine recombinante Eg1814
• Nom complet: tumor necrosis factor receptor superfamily, member 13b
• Masse moléculaire calculée: 27 kDa
• Poids moléculaire observé: 30-32 kDa
• Numéro d’acquisition GenBank: NM_021349.1
• Symbole du gène: Tnfrsf13b
• Identification du gène (NCBI): 57916
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

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