Anticorps Polyclonal de lapin anti-TACSTD2/TROP2

TACSTD2/TROP2 Polyclonal Antibody for WB, IHC, IF/ICC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, IF/ICC, ELISA

Conjugaison

Non conjugué

N° de cat : 27360-1-PBS

Synonymes

TACSTD2, M1S1, GA733-1, GA733 1, GA733

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Galerie de données de validation

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  WB analysis of HaCaT using 27360-1-AP (same clone as 27360-1-PBS)

  HaCaT cells were subjected to SDS PAGE followed by western blot with 27360-1-AP (TACSTD2 antibody) at dilution of 1:1200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 27360-1-AP (same clone as 27360-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27360-1-AP (TACSTD2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 27360-1-AP (same clone as 27360-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27360-1-AP (TACSTD2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 27360-1-AP (same clone as 27360-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 27360-1-AP (TACSTD2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 27360-1-AP (same clone as 27360-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 27360-1-AP (TACSTD2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

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  IF Staining of HaCaT using 27360-1-AP (same clone as 27360-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed HaCaT cells using TACSTD2/TROP2 antibody (27360-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27360-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27360-1-PBS cible TACSTD2/TROP2 dans les applications de WB, IHC, IF/ICC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TACSTD2/TROP2 Protéine recombinante Ag25769
• Nom complet: tumor-associated calcium signal transducer 2
• Masse moléculaire calculée: 36 kDa
• Poids moléculaire observé: 45-55 kDa
• Numéro d’acquisition GenBank: BC009409
• Symbole du gène: TROP2
• Identification du gène (NCBI): 4070
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).

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