Anticorps Monoclonal anti-TACSTD2/TROP2

TACSTD2/TROP2 Monoclonal Antibody for WB, IHC, IF/ICC, IF-P, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, souris

Applications

WB, IHC, IF/ICC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

5A6B1

N° de cat : 68141-1-PBS

Synonymes

TACSTD2, 5A6B1, Cell surface glycoprotein Trop-2, EGP 1, GA733

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Galerie de données de validation

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  WB analysis of HaCaT using 68141-1-Ig (same clone as 68141-1-PBS)

  HaCaT cells were subjected to SDS PAGE followed by western blot with 68141-1-Ig (TACSTD2/TROP2 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68141-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 68141-1-Ig (same clone as 68141-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 68141-1-Ig (TACSTD2/TROP2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68141-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 68141-1-Ig (same clone as 68141-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 68141-1-Ig (TACSTD2/TROP2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68141-1-PBS in a different storage buffer formulation.

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  IHC staining of human cervical cancer using 68141-1-Ig (same clone as 68141-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 68141-1-Ig (TACSTD2 antibody) at dilution of 1:16000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68141-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse skin using 68141-1-Ig (same clone as 68141-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse skin tissue using TACSTD2/TROP2 antibody (68141-1-Ig, Clone: 5A6B1 ) at dilution of 1:100 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68141-1-PBS in a different storage buffer formulation.

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  IF Staining of HaCaT using 68141-1-Ig (same clone as 68141-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed HaCaT cells using TACSTD2/TROP2 antibody (68141-1-Ig, Clone: 5A6B1 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 68141-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68141-1-PBS cible TACSTD2/TROP2 dans les applications de WB, IHC, IF/ICC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TACSTD2/TROP2 Protéine recombinante Ag25775
• Nom complet: tumor-associated calcium signal transducer 2
• Masse moléculaire calculée: 36 kDa
• Poids moléculaire observé: 40-50 kDa
• Numéro d’acquisition GenBank: BC009409
• Symbole du gène: TROP2
• Identification du gène (NCBI): 4070
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).

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