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Anticorps Recombinant de lapin anti-TACSTD2/TROP2

TACSTD2/TROP2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250382A12

N° de cat : 98465-2-PBS

Synonymes

TACSTD2, Cell surface glycoprotein Trop-2, EGP 1, GA733, GA733 1

Galerie de données de validation

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  • Flow cytometry (FC) experiment of MCF-7 cells using Anti-Human TACSTD2/TROP2 Rabbit Recombinant Antibo (98465-2-RR)

    FC experiment of MCF-7 using 98465-2-RR (same clone as 98465-2-PBS)

    1x10^6 MCF-7 cells were surface stained with 0.25 ug Anti-Human TACSTD2/TROP2 Rabbit RecAb (98465-2-RR, Clone: 250382A12) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98465-2-PBS in a different storage buffer formulation.

Informations sur le produit

98465-2-PBS cible TACSTD2/TROP2 dans les applications de FC et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène TACSTD2/TROP2 Protéine recombinante Eg3329
Nom complet tumor-associated calcium signal transducer 2
Masse moléculaire calculée 36 kDa
Numéro d’acquisition GenBankBC009409
Symbole du gène TROP2
Identification du gène (NCBI) 4070
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C.

Informations générales

Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).

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