Anticorps Monoclonal anti-TACSTD2/TROP2

TACSTD2/TROP2 Monoclonal Antibody for IF-P

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain, souris

Applications

IF-P

Conjugaison

APC Fluorescent Dye

CloneNo.

5A6B1

N° de cat : APC-68141

Synonymes

TACSTD2, GA733-1, GA733 1, GA733, EGP 1

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Galerie de données de validation

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  IF Staining of mouse skin using APC-68141

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse skin tissue using APC TACSTD2/TROP2 antibody (APC-68141, Clone: 5A6B1 ) at dilution of 1:200. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IF Staining of mouse skin using APC-68141

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse skin tissue using APC TACSTD2/TROP2 antibody (APC-68141, Clone: 5A6B1 ) at dilution of 1:200. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Applications testées

• Résultats positifs en IF-P: tissu cutané de souris,

Dilution recommandée

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

APC-68141 cible TACSTD2/TROP2 dans les applications de IF-P et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TACSTD2/TROP2 Protéine recombinante Ag25775
• Nom complet: tumor-associated calcium signal transducer 2
• Masse moléculaire calculée: 36 kDa
• Poids moléculaire observé: 40-50 kDa
• Numéro d’acquisition GenBank: BC009409
• Symbole du gène: TROP2
• Identification du gène (NCBI): 4070
• Conjugaison: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. 20ul contiennent 0,1% de BSA.

Informations générales

Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).

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