Anticorps Polyclonal de lapin anti-TAP2

TAP2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 10161-1-PBS

Synonymes

PSF-2, PSF2, EC:7.4.2.14, ATP-binding cassette sub-family B member 3, APT2

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Galerie de données de validation

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  WB analysis using 10161-1-AP (same clone as 10161-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10161-1-AP (TAP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10161-1-PBS in a different storage buffer formulation.

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  IHC staining of human intrahepatic cholangiocarcinoma using 10161-1-AP (same clone as 10161-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 10161-1-AP (TAP2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10161-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary cancer using 10161-1-AP (same clone as 10161-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 10161-1-AP (TAP2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10161-1-PBS in a different storage buffer formulation.

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Informations sur le produit

10161-1-PBS cible TAP2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TAP2 Protéine recombinante Ag0190
• Nom complet: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
• Masse moléculaire calculée: 76 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC002751
• Symbole du gène: TAP2
• Identification du gène (NCBI): 6891
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TAP2, also known as APT2, ABCB3, is a member of the superfamily of ATP-binding cassette (ABC) transporters. TAP2 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules (PMID: 25656091). Mutations in TAP2 may be associated with Bare lymphocyte syndrome 1 (BLS1) and schizophrenia(PMID: 7517574, 24365204).

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