Anticorps Polyclonal de lapin anti-TAX1BP1

• Phare
• Validé par KD/KO

TAX1BP1 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14424-1-PBS

Synonymes

TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105

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Galerie de données de validation

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  WB analysis using 14424-1-AP (same clone as 14424-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14424-1-AP (TAX1BP1 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14424-1-PBS in a different storage buffer formulation.

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  IHC staining of human skin cancer using 14424-1-AP (same clone as 14424-1-PBS)

  Immunohistochemical analysis of paraffin-embedded skin cancer slide using 14424-1-AP (TAX1BP1 antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14424-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 14424-1-AP (same clone as 14424-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using TAX1BP1 antibody (14424-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 14424-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14424-1-PBS cible TAX1BP1 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TAX1BP1 Protéine recombinante Ag5789
• Nom complet: Tax1 (human T-cell leukemia virus type I) binding protein 1
• Masse moléculaire calculée: 91 kDa
• Poids moléculaire observé: 90 kDa
• Numéro d’acquisition GenBank: BC050358
• Symbole du gène: TAX1BP1
• Identification du gène (NCBI): 8887
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5.

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