Anticorps Monoclonal anti-TAX1BP1

TAX1BP1 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1H2D10

N° de cat : 60466-1-PBS

Synonymes

TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105, 1H2D10

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Galerie de données de validation

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  WB analysis using 60466-1-Ig (same clone as 60466-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60466-1-Ig (TAX1BP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60466-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60466-1-PBS cible TAX1BP1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TAX1BP1 Protéine recombinante Ag6279
• Nom complet: Tax1 (human T-cell leukemia virus type I) binding protein 1
• Masse moléculaire calculée: 91 kDa
• Poids moléculaire observé: 68 kDa, 85 kDa
• Numéro d’acquisition GenBank: BC050358
• Symbole du gène: TAX1BP1
• Identification du gène (NCBI): 8887
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms, this antibody recognizes both TXBP151-L and TXBP151-S.

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