Anticorps Recombinant de lapin anti-TBX21/T-bet

TBX21/T-bet Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240849C1

N° de cat : 83804-6-PBS

Synonymes

TBX21, TBX21,T-bet, TBX 21, T-box transcription factor TBX21, T-box protein 21

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Galerie de données de validation

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  WB analysis of CTLL-2 using 83804-6-RR (same clone as 83804-6-PBS)

  CTLL-2 cells were subjected to SDS PAGE followed by western blot with 83804-6-RR (TBX21/T-bet antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83804-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83804-6-RR

  Biolayer interferometry (BLl) kinetic assays of 83804-6-RR against Human TBX21,T-bet were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83804-6-PBS cible TBX21/T-bet dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TBX21/T-bet Protéine recombinante Ag4618
• Nom complet: T-box 21
• Masse moléculaire calculée: 535 aa, 58 kDa
• Poids moléculaire observé: 60-65 kDa
• Numéro d’acquisition GenBank: BC039739
• Symbole du gène: TBX21/T-bet
• Identification du gène (NCBI): 30009
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TBX21 is a transcription factor that drives the Th1 immune response primarily through promoting expression of the IFN-γ gene. TBX21 initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. It has also been shown to play an influential role in inflammatory processes such as inflammatory bowel disease, autoimmune diseases such as rheumatoid arthritis, and immune-mediated conditions like asthma.

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